CDC warns of deadly drug 100 times more potent than fentanyl

Fentanyl has made headlines for driving overdose deaths, but the Centers for Disease Control and Prevention (CDC) is warning of the rise of an even deadlier drug.

Last year, nearly 70% of all U.S. overdose deaths were attributed to illegally manufactured fentanyls (IMFs). One of those was carfentanil, an altered version of fentanyl that is said to be 100 times more potent, the CDC warned in a Dec. 5 alert.

Deaths from carfentanil rose by more than 700% in the past year, according to the same source — there were 29 deadly overdoses between January and June 2023, and 238 in that same time frame in 2024.

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This data came from the CDC’s State Unintentional Drug Overdose Reporting System (SUDORS).

The numbers could actually be higher, as the 2024 data is preliminary and not all overdose deaths have been reported, the agency noted.